metformin ep impurity a

Dicyandiamide (DCDA) is a kind of White crystal. Relative density is 1.40. Melting point is 209-212°C. It is soluble in water and alcohol, slightly insoluble in aether and benzene. It is Stable in dry condition. Not flammable. Dicyandiamide is an intermediate for synthesis of medicines. It is used in the production of a wide range of organic chemicals, including slow and continuous nitrogen release fertilizer, pesticides, dye fixing, fire proofing agents, epoxy laminates for circuit boards, powder coatings and adhesives, water treatment chemicals, leather and rubber chemicals, explosives and pharmaceuticals.

Pharmaceutical grade dicyandiamide is mainly used in the production of active pharmaceutical ingredients (APIs), which are used in production of metformin, a preferred drug for the treatment of type 2 diabetes mellitus. Metformin is also used in the treatment of excess weight and obesity. Metformin can improve glucose tolerance in diabetic patients, lowering basal and postprandial plasma glucose. Asia Pacific is the key metformin producing and exporting region across the globe.